121 East Grand Avenue Project


SCH Number
Lead Agency
City of South San Francisco
Document Title
121 East Grand Avenue Project
Document Type
MND - Mitigated Negative Declaration
Present Land Use
Hotel, Transit Office/ R&D Core.
Document Description
The Project proposes the construction and operation of a 17-story mixed-use life science, office and community serving retail project on a 2.91-acre Project site at 121 East Grand Avenue in South San Francisco, CA. The 943,965 sq ft building includes 836,865 sq ft of research development/office and 107,100 sq ft of community amenities. The Project also includes 41,528 sq ft of landscaped public plazas, 255,407 sq ft of vehicle parking, 250 bicycle parking spaces, and 35,249 sq ft of loading/storage and support. The two-story podium would be designed, landscaped and furnished to provide seating, and gathering areas, and various access points to the building. The first two floors of the building, Level 1 and Level 2, would provide public amenities and Floors three through 17 would include research and development and office uses. Vehicle parking is proposed primarily in two below-grade levels and a small portion on Level 1 (ADA parking, valet, etc.). A 700 ft long lighted and landscaped bicycle and pedestrian trail would traverse the site from Poletti Way, along the western, southern, and eastern frontages of the Project site to Grand Avenue and East Grand Avenue. An additional 300 ft of pedestrian pathways are proposed on the Project site.

Contact Information

Billy Gross
Agency Name
City of South San Francisco
Job Title
Principal Planner
Contact Types
Lead/Public Agency


South San Francisco
San Mateo
Citywide, San Francisco Bay Area
Cross Streets
121 East Grand Avenue
Total Acres
Parcel #
015 024 230
State Highways
US Route 101 and 82
Caltrain/ Union Pacific
San Francisco International
Colma Creek, San Francisco Bay

Notice of Completion

State Review Period Start
State Review Period End
State Reviewing Agencies
California Air Resources Board (ARB), California Department of Fish and Wildlife, Bay Delta Region 3 (CDFW), California Department of Fish and Wildlife, Marin Region 7 (CDFW), California Department of Forestry and Fire Protection (CAL FIRE), California Department of Parks and Recreation, California Department of Transportation, District 4 (DOT), California Department of Transportation, Division of Aeronautics (DOT), California Department of Transportation, Division of Transportation Planning (DOT), California Department of Water Resources (DWR), California Highway Patrol (CHP), California Native American Heritage Commission (NAHC), California Natural Resources Agency, California Public Utilities Commission (CPUC), California Regional Water Quality Control Board, San Francisco Bay Region 2 (RWQCB), California State Lands Commission (SLC), Department of Toxic Substances Control, Office of Historic Preservation, San Francisco Bay Conservation and Development Commission (BCDC), State Water Resources Control Board, Division of Drinking Water, State Water Resources Control Board, Division of Water Quality, California Department of Conservation (DOC)
State Reviewing Agency Comments
California Department of Conservation (DOC)
Development Types
Office (Mixed-use life science, office and retail.)(Sq. Ft. 943965, Acres 2.91, Employees 2339)
Local Actions
General Plan Amendment, Use Permit, Zoning Ordinance Amendment
Project Issues
Aesthetics, Agriculture and Forestry Resources, Air Quality, Biological Resources, Cultural Resources, Cumulative Effects, Drainage/Absorption, Economics/Jobs, Energy, Flood Plain/Flooding, Geology/Soils, Greenhouse Gas Emissions, Growth Inducement, Hazards & Hazardous Materials, Hydrology/Water Quality, Land Use/Planning, Mandatory Findings of Significance, Mineral Resources, Noise, Population/Housing, Public Services, Recreation, Schools/Universities, Sewer Capacity, Solid Waste, Transportation, Tribal Cultural Resources, Utilities/Service Systems, Vegetation, Wildfire


Notice of Completion [NOC] Transmittal form
State Comment Letters [Comments from state reviewing agencies]

Disclaimer: The Governor’s Office of Planning and Research (OPR) accepts no responsibility for the content or accessibility of these documents. To obtain an attachment in a different format, please contact the lead agency at the contact information listed above. You may also contact the OPR via email at state.clearinghouse@opr.ca.gov or via phone at (916) 445-0613. For more information, please visit OPR’s Accessibility Site.

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