To determine the effects of clethodim, a monocot-specific herbicide, on Nipomo Mesa lupine. The project will consist of two consecutive trials. Trial 1 will test the effects of an herbicide mixture on Nipomo Mesa lupine. If effects are observed on Nipomo Mesa lupine in Trial 1, a second trial (Trial 2) will be conducted to test each of the components of the herbicide mixture individually on Nipomo Mesa lupine. For Trial 1, Permittee will germinate 120 seedlings of Nipomo Mesa lupine from seeds stored at the CCBER facility. Propagated plants will be subject to different herbicide treatments during the seedling stage or the flowering stage. Treatments will be applied so they mimic both aerial broadcast application using larger droplets and ground application using a fine spray. The proposed brands for herbicide and adjuvants were selected because they are currently being used within the Nipomo-Guadalupe Dunes Complex to control perennial veldt grass in occupied Nipomo Mesa lupine habitat. These products include the clethodim based herbicide (Vaquero), a modified vegetable oil-based surfactant (Renegade-EA) and drift management agent (Crosshair). All plants will be grown to maturity and flowering, fruiting, and seed set will be documented. A subset of seeds from each treatment will be tested for viability. By combining Vaquero, Renegade_EA, and Crosshair in the herbicide mixture, it will not be possible to determine which product is responsible for any negative effects that may occur. Therefore, if any negative effects are observed during Trial 1, the study will be repeated using each product individually during Trial 2. If negative effects are not observed during Trial 1, the Trial 2 will not be conducted. Should Trial 2 be necessary, an additional 280 plants will be germinated for herbicide treatment.