A COMMUNITY PLAN AMENDMENT to transfer development intensity rights (3,744 average daily trips or “ADT”) from University Community Plan Area Subarea 37 (City Ownership) to newly created Subareas 102 and Subarea 10; REZONE to change the zoning from RS-1-14 (Residential--Single-Family Unit) to EMX-2 (Employment Mixed-Use); a GENERAL PLAN AMENDMENT, as the University Community Plan is a component of the City’s General Plan Land Use and Community Planning Element; a SPECIFIC PLAN AMENDMENT to remove the project site from the Nexus Technology Centre Specific Plan; and a PLANNED DEVELOPMENT PERMIT for the demolition of three existing scientific research buildings totaling approximately 138,400 square feet; and the construction of two, four-story scientific research and development (R&D) buildings totaling approximately 369,878 square feet with associated accessory uses. The project would consist of approximately 310,416 square feet of R&D uses and 59,462 feet of accessory/amenity space. Additionally, three levels of subterranean parking with approximately 938 parking spaces are proposed. The approximately 3.97-acre site is located on three parcels which include 9363, 9373, and 9393 Towne Centre Drive and is designated as Industrial Employment per the General Plan and designated Scientific Research and zoned RS-1-14 in the University Community Plan. The site is within University Community Plan Area Subarea 37. The project site is within the Airport Land Use Compatibility Overlay Zone (Marine Corps Air Station [MCAS] Miramar); the Airport Influence Area (MCAS Miramar-Review Area 1); the Federal Aviation Administration (FAA) Part 77 Noticing Area; Airport Noise Contours (MCAS Miramar-60-65 Community Noise Equivalent Level [CNEL]); the Community Plan Implementation Overlay Zone type A (CPIOZ-A); the Parking Impact Overlay Zone (Campus); the Parking Standards Transit Priority Area; Prime Industrial Lands; and the Transit Priority Area.